Pseudomonas aeruginosa PAO1, PA1867 (xphA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1867
Name
xphA
Synonym: xphA
Replicon chromosome
Genomic location 2028454 - 2028981 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250558.1
GI 15597064
Affymetrix PA1867_at
Entrez 878024
GenBank AAG05256.1
INSDC AAG05256.1
NCBI Locus Tag PA1867
protein_id(GenBank) gb|AAG05256.1|AE004613_1|gnl|PseudoCAP|PA1867
TIGR NTL03PA01868
UniParc UPI00000C54DF
UniProtKB Acc Q9I2M8
UniProtKB ID Q9I2M8_PSEAE
UniRef100 UniRef100_W0YPD5
UniRef50 UniRef50_W0YPD5
UniRef90 UniRef90_W0YPD5

Product

Feature Type CDS
Coding Frame 1
Product Name
XphA
Product Name Confidence: Class 1
Synonyms XphA
Evidence for Translation
Charge (pH 7) 9.07
Kyte-Doolittle Hydrophobicity Value 0.094
Molecular Weight (kDa) 18.5
Isoelectric Point (pI) 11.01

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 2 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003535 (299 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1867
Search term: xphA
Search term: XphA

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
XphA/XqhA, a novel GspCD subunit for type II secretion in Pseudomonas aeruginosa.
Michel GP, Durand E, Filloux A
J Bacteriol 2007 May;189(10):3776-83
PubMed ID: 17351035