Pseudomonas aeruginosa PAO1, PA1874

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1874
Name
Replicon chromosome
Genomic location 2036441 - 2043847 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs
Commentinvolved in biofilm-specific resistance to a subset of antibiotics

Cross-References

RefSeq NP_250565.1
GI 15597071
Affymetrix PA1874_at
Entrez 882263
GenBank AAG05263.1
INSDC AAG05263.1
NCBI Locus Tag PA1874
protein_id(GenBank) gb|AAG05263.1|AE004613_8|gnl|PseudoCAP|PA1874
TIGR NTL03PA01875
UniParc UPI00000C54E3
UniProtKB Acc Q9I2M3
UniProtKB ID Q9I2M3_PSEAE
UniRef100 UniRef100_Q9I2M3
UniRef50 UniRef50_Q9I2M3
UniRef90 UniRef90_Q9I2M3

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -193.11
Kyte-Doolittle Hydrophobicity Value 0.000
Molecular Weight (kDa) 238.4
Isoelectric Point (pI) 3.13

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 126 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001201 (1272 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1874

Human Homologs

References

Involvement of a novel efflux system in biofilm-specific resistance to antibiotics.
Zhang L, Mah TF
J Bacteriol 2008 Jul;190(13):4447-52
PubMed ID: 18469108