Pseudomonas aeruginosa PAO1, PA1910 (femA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1910
Name
femA
Synonym: ufrA
Replicon chromosome
Genomic location 2081853 - 2084267 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250600.1
GI 15597106
Affymetrix PA1910_at
Entrez 880720
GenBank AAG05298.1
INSDC AAG05298.1
NCBI Locus Tag PA1910
protein_id(GenBank) gb|AAG05298.1|AE004617_2|gnl|PseudoCAP|PA1910
TIGR NTL03PA01910
UniParc UPI00000C5500
UniProtKB Acc Q9I2J4
UniProtKB ID Q9I2J4_PSEAE
UniRef100 UniRef100_Q9I2J4
UniRef50 UniRef50_Q9I2J4
UniRef90 UniRef90_Q9I2J4

Product

Feature Type CDS
Coding Frame 1
Product Name
ferric-mycobactin receptor, FemA
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -5.08
Kyte-Doolittle Hydrophobicity Value -0.273
Molecular Weight (kDa) 86.4
Isoelectric Point (pI) 6.27

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 219 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003507 (512 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1910
Search term: femA

Human Homologs

References

The TonB-dependent ferrichrome receptor FcuA of Yersinia enterocolitica: evidence against a strict co-evolution of receptor structure and substrate specificity.
Koebnik R, Hantke K, Braun V
Mol Microbiol 1993 Feb;7(3):383-93
PubMed ID: 8384682
Gene regulation of siderophore-mediated iron acquisition in Pseudomonas: not only the Fur repressor.
Venturi V, Weisbeek P, Koster M
Mol Microbiol 1995 Aug;17(4):603-10
PubMed ID: 8801415
Characterization of five novel Pseudomonas aeruginosa cell-surface signalling systems.
Llamas MA, Mooij MJ, Sparrius M, Vandenbroucke-Grauls CM, Ratledge C, Bitter W
Mol Microbiol 2008 Jan;67(2):458-72
PubMed ID: 18086184