Pseudomonas aeruginosa PAO1, PA1912 (femI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1912
Name
femI
Replicon chromosome
Genomic location 2085423 - 2085929 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250602.1
GI 15597108
Affymetrix PA1912_at
DNASU PaCD00006860
Entrez 878255
GenBank AAG05300.1
INSDC AAG05300.1
NCBI Locus Tag PA1912
protein_id(GenBank) gb|AAG05300.1|AE004617_4|gnl|PseudoCAP|PA1912
TIGR NTL03PA01912
UniParc UPI00000C5502
UniProtKB Acc Q9I2J2
UniProtKB ID Q9I2J2_PSEAE
UniRef100 UniRef100_W0YSL2
UniRef50 UniRef50_G8PZ98
UniRef90 UniRef90_A6V6P7

Product

Feature Type CDS
Coding Frame 1
Product Name
ECF sigma factor, FemI
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -1.87
Kyte-Doolittle Hydrophobicity Value -0.218
Molecular Weight (kDa) 19.1
Isoelectric Point (pI) 6.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 304 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000463 (1798 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1912
Search term: femI

Human Homologs

References

Role for the outer membrane ferric siderophore receptor PupB in signal transduction across the bacterial cell envelope.
Koster M, van Klompenburg W, Bitter W, Leong J, Weisbeek P
EMBO J 1994 Jun 15;13(12):2805-13
PubMed ID: 8026465
Characterization of five novel Pseudomonas aeruginosa cell-surface signalling systems.
Llamas MA, Mooij MJ, Sparrius M, Vandenbroucke-Grauls CM, Ratledge C, Bitter W
Mol Microbiol 2008 Jan;67(2):458-72
PubMed ID: 18086184