Pseudomonas aeruginosa PAO1, PA2006

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2006
Name
Replicon chromosome
Genomic location 2194058 - 2195410 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 6 transposon mutants in orthologs

Cross-References

RefSeq NP_250696.1
GI 15597202
Affymetrix PA2006_at
Entrez 878919
GenBank AAG05394.1
INSDC AAG05394.1
NCBI Locus Tag PA2006
protein_id(GenBank) gb|AAG05394.1|AE004627_2|gnl|PseudoCAP|PA2006
TIGR NTL03PA02006
UniParc UPI00000C5555
UniProtKB Acc Q9I2A3
UniProtKB ID Q9I2A3_PSEAE
UniRef100 UniRef100_Q9I2A3
UniRef50 UniRef50_A0A077JUK3
UniRef90 UniRef90_A0A077JUK3

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 4.80
Kyte-Doolittle Hydrophobicity Value 0.788
Molecular Weight (kDa) 48.1
Isoelectric Point (pI) 8.71

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 440 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000234 (2404 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2006

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Identification of the pcaRKF gene cluster from Pseudomonas putida: involvement in chemotaxis, biodegradation, and transport of 4-hydroxybenzoate.
Harwood CS, Nichols NN, Kim MK, Ditty JL, Parales RE
J Bacteriol 1994 Nov;176(21):6479-88
PubMed ID: 7961399
The pca-pob supraoperonic cluster of Acinetobacter calcoaceticus contains quiA, the structural gene for quinate-shikimate dehydrogenase.
Elsemore DA, Ornston LN
J Bacteriol 1994 Dec;176(24):7659-66
PubMed ID: 8002591