Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2019
|
Name |
mexX
Synonym: mexG Synonym: amrA |
Replicon | chromosome |
Genomic location | 2211322 - 2212512 (- strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
RefSeq | NP_250709.1 |
GI | 15597215 |
Affymetrix | PA2019_at |
Entrez | 878839 |
GenBank | AAG05407.1 |
INSDC | AAG05407.1 |
NCBI Locus Tag | PA2019 |
protein_id(GenBank) | gb|AAG05407.1|AE004628_5|gnl|PseudoCAP|PA2019 |
TIGR | NTL03PA02019 |
UniParc | UPI00000D4247 |
UniProtKB Acc | G3XD21 |
UniProtKB ID | G3XD21_PSEAE |
UniRef100 | UniRef100_G3XD21 |
UniRef50 | UniRef50_G3XD21 |
UniRef90 | UniRef90_G3XD21 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexX precursor
|
Synonyms |
RND multidrug efflux membrane fusion protein precursor |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -2.05 |
Kyte-Doolittle Hydrophobicity Value | -0.059 |
Molecular Weight (kDa) | 42.1 |
Isoelectric Point (pI) | 6.19 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 376 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003421 (311 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2019
Search term: mexX
|
Efflux-mediated aminoglycoside and macrolide resistance in Burkholderia pseudomallei.
Moore RA, DeShazer D, Reckseidler S, Weissman A, Woods DE
Antimicrob Agents Chemother 1999 Mar;43(3):465-70
PubMed ID: 10049252
|
MexXY multidrug efflux system of Pseudomonas aeruginosa.
Morita Y, Tomida J, Kawamura Y
Front Microbiol 2012;3:408
PubMed ID: 23233851
|
Induction of the MexXY efflux pump in Pseudomonas aeruginosa is dependent on drug-ribosome interaction.
Jeannot K, Sobel ML, El Garch F, Poole K, Plésiat P
J Bacteriol 2005 Aug;187(15):5341-6
PubMed ID: 16030228
|