Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2200
|
Name |
|
Replicon | chromosome |
Genomic location | 2418723 - 2420318 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | Overexpression of PA2200 results in impaired TTSS-mediated cytotoxicity |
RefSeq | NP_250890.1 |
GI | 15597396 |
Affymetrix | PA2200_at |
Entrez | 881519 |
GenBank | AAG05588.1 |
INSDC | AAG05588.1 |
NCBI Locus Tag | PA2200 |
protein_id(GenBank) | gb|AAG05588.1|AE004646_9|gnl|PseudoCAP|PA2200 |
TIGR | NTL03PA02200 |
UniParc | UPI00000C5602 |
UniProtKB Acc | Q9I1R7 |
UniProtKB ID | Q9I1R7_PSEAE |
UniRef100 | UniRef100_Q9I1R7 |
UniRef50 | UniRef50_W1MMD6 |
UniRef90 | UniRef90_S0IK80 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Cyclic-guanylate-specific phosphodiesterase
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -5.81 |
Kyte-Doolittle Hydrophobicity Value | -0.021 |
Molecular Weight (kDa) | 58.3 |
Isoelectric Point (pI) | 6.04 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 402 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003283 (345 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2200
Search term: Cyclic-guanylate-specific phosphodiesterase
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence.
Kulasakara H, Lee V, Brencic A, Liberati N, Urbach J, Miyata S, Lee DG, Neely AN, Hyodo M, Hayakawa Y, Ausubel FM, Lory S
Proc Natl Acad Sci U S A 2006 Feb 21;103(8):2839-44
PubMed ID: 16477007
|