Pseudomonas aeruginosa PAO1, PA2214

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2214
Name
Replicon chromosome
Genomic location 2433748 - 2435070 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250904.1
GI 15597410
Affymetrix PA2214_at
Entrez 878579
GenBank AAG05602.1
INSDC AAG05602.1
NCBI Locus Tag PA2214
protein_id(GenBank) gb|AAG05602.1|AE004648_1|gnl|PseudoCAP|PA2214
TIGR NTL03PA02214
UniParc UPI00000C560F
UniProtKB Acc Q9I1Q3
UniProtKB ID Q9I1Q3_PSEAE
UniRef100 UniRef100_W0YSC1
UniRef50 UniRef50_A4FLW8
UniRef90 UniRef90_V6AFV8

Product

Feature Type CDS
Coding Frame 1
Product Name
putative L-lyxonate transporter
Product Name Confidence: Class 2
Synonyms probable MFS transporter
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 9.00
Kyte-Doolittle Hydrophobicity Value 0.670
Molecular Weight (kDa) 47.3
Isoelectric Point (pI) 9.31

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 220 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003275 (459 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2214

Human Homologs

References

Discovery of a novel L-lyxonate degradation pathway in Pseudomonas aeruginosa PAO1.
Ghasempur S, Eswaramoorthy S, Hillerich BS, Seidel RD, Swaminathan S, Almo SC, Gerlt JA
Biochemistry 2014 May 27;53(20):3357-66
PubMed ID: 24831290