Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2254
|
Name |
pvcA
|
Replicon | chromosome |
Genomic location | 2482045 - 2483031 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_250944.1 |
GI | 15597450 |
Affymetrix | PA2254_pvcA_at |
DNASU | PaCD00006996 |
Entrez | 878099 |
GenBank | AAG05642.1 |
INSDC | AAG05642.1 |
NCBI Locus Tag | PA2254 |
protein_id(GenBank) | gb|AAG05642.1|AE004651_4|gnl|PseudoCAP|PA2254 |
TIGR | NTL03PA02254 |
UniParc | UPI00000C5631 |
UniProtKB Acc | Q9I1L5 |
UniProtKB ID | Q9I1L5_PSEAE |
UniRef100 | UniRef100_Q9I1L5 |
UniRef50 | UniRef50_Q9I1L5 |
UniRef90 | UniRef90_Q9I1L5 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
paerucumarin biosynthesis protein PvcA
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -1.89 |
Kyte-Doolittle Hydrophobicity Value | -0.258 |
Molecular Weight (kDa) | 37.1 |
Isoelectric Point (pI) | 6.61 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
3E59 | TRANSFERASE | 08/13/08 | Crystal structure of the PvcA (PA2254) protein from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 2.1 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 21 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003235 (309 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2254
Search term: pvcA
Search term: paerucumarin biosynthesis protein PvcA
|
Novel pyoverdine biosynthesis gene(s) of Pseudomonas aeruginosa PAO.
Stintzi A, Cornelis P, Hohnadel D, Meyer JM, Dean C, Poole K, Kourambas S, Krishnapillai V
Microbiology (Reading) 1996 May;142 ( Pt 5):1181-1190
PubMed ID: 8704959
|
The pvc gene cluster of Pseudomonas aeruginosa: role in synthesis of the pyoverdine chromophore and regulation by PtxR and PvdS.
Stintzi A, Johnson Z, Stonehouse M, Ochsner U, Meyer JM, Vasil ML, Poole K
J Bacteriol 1999 Jul;181(13):4118-24
PubMed ID: 10383985
|
Paerucumarin, a new metabolite produced by the pvc gene cluster from Pseudomonas aeruginosa.
Clarke-Pearson MF, Brady SF
J Bacteriol 2008 Oct;190(20):6927-30
PubMed ID: 18689486
|
Three-dimensional structures of Pseudomonas aeruginosa PvcA and PvcB, two proteins involved in the synthesis of 2-isocyano-6,7-dihydroxycoumarin.
Drake EJ, Gulick AM
J Mol Biol 2008 Dec 5;384(1):193-205
PubMed ID: 18824174
|