Pseudomonas aeruginosa PAO1, PA2388 (fpvR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2388
Name
fpvR
Replicon chromosome
Genomic location 2641035 - 2642030 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251078.1
GI 15597584
Affymetrix PA2388_at
Entrez 882258
GenBank AAG05776.1
INSDC AAG05776.1
NCBI Locus Tag PA2388
protein_id(GenBank) gb|AAG05776.1|AE004665_3|gnl|PseudoCAP|PA2388
TIGR NTL03PA02388
UniParc UPI00000C56A7
UniProtKB Acc Q9I192
UniProtKB ID Q9I192_PSEAE
UniRef100 UniRef100_Q9I192
UniRef50 UniRef50_Q9I192
UniRef90 UniRef90_Q9I192

Product

Feature Type CDS
Coding Frame 1
Product Name
FpvR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.86
Kyte-Doolittle Hydrophobicity Value -0.397
Molecular Weight (kDa) 37.0
Isoelectric Point (pI) 6.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 139 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003139 (481 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2388
Search term: fpvR
Search term: FpvR

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295