Pseudomonas aeruginosa PAO1, PA2408 (fpvD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA2408
Name
fpvD
Replicon chromosome
Genomic location 2691110 - 2691865 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_251098.1
GI 15597604
Affymetrix PA2408_at
Entrez 879637
GenBank AAG05796.1
INSDC AAG05796.1
NCBI Locus Tag PA2408
protein_id(GenBank) gb|AAG05796.1|AE004668_6|gnl|PseudoCAP|PA2408
TIGR NTL03PA02408
UniParc UPI00000C56B7
UniProtKB Acc Q9I173
UniProtKB ID Q9I173_PSEAE
UniRef100 UniRef100_Q9I173
UniRef50 UniRef50_D7HYC2
UniRef90 UniRef90_Q9I173

Product

Feature Type CDS
Coding Frame 1
Product Name
FpvD
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) 3.84
Kyte-Doolittle Hydrophobicity Value -0.000
Molecular Weight (kDa) 27.1
Isoelectric Point (pI) 8.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003124 (498 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2408
Search term: fpvD
Search term: FpvD

Human Homologs

Ensembl 86, assembly GRCh38.p7
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 9.4e-10
Percent Identity: 28.4

Transposon Insertions in PAO1

Type ISlacZ/hah insertion site
Mutant ID UWGC: 8132
Genomic Position 2691649
Position in ORF 540(756)
Reference 14617778

Transposon Insertions in Orthologs

References

Iron Release from the Siderophore Pyoverdine in Pseudomonas aeruginosa Involves Three New Actors: FpvC, FpvG, and FpvH.
Ganne G, Brillet K, Basta B, Roche B, Hoegy F, Gasser V, Schalk IJ
ACS Chem. Biol. 2017 Apr;12(4):1056-1065
PubMed ID: 28192658
An ABC transporter with two periplasmic binding proteins involved in iron acquisition in Pseudomonas aeruginosa.
Brillet K, Ruffenach F, Adams H, Journet L, Gasser V, Hoegy F, Guillon L, Hannauer M, Page A, Schalk IJ
ACS Chem. Biol. 2012 Dec;7(12):2036-45
PubMed ID: 23009327