Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2449
|
Name |
gcsR
|
Replicon | chromosome |
Genomic location | 2750128 - 2751663 (- strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Comment | Responsible for transcriptional activation of the gcvH2-gcvP2-glyA2-sdaA-gcvT2 operon that encodes genes required for glycine metabolism |
RefSeq | NP_251139.1 |
GI | 15597645 |
Affymetrix | PA2449_at |
Entrez | 882923 |
GenBank | AAG05837.1 |
INSDC | AAG05837.1 |
NCBI Locus Tag | PA2449 |
protein_id(GenBank) | gb|AAG05837.1|AE004672_5|gnl|PseudoCAP|PA2449 |
TIGR | NTL03PA02449 |
UniParc | UPI00000C56DB |
UniProtKB Acc | Q9I133 |
UniProtKB ID | Q9I133_PSEAE |
UniRef100 | UniRef100_W1MJR5 |
UniRef50 | UniRef50_D7HWM2 |
UniRef90 | UniRef90_A6V526 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
GcsR
|
Synonyms |
transcriptional regulator |
Evidence for Translation | |
Charge (pH 7) | -6.78 |
Kyte-Doolittle Hydrophobicity Value | -0.042 |
Molecular Weight (kDa) | 55.7 |
Isoelectric Point (pI) | 6.17 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 449 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003090 (505 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2449
Search term: gcsR
Search term: GcsR
|
Gene PA2449 is essential for glycine metabolism and pyocyanin biosynthesis in Pseudomonas aeruginosa PAO1.
Lundgren BR, Thornton W, Dornan MH, Villegas-Peñaranda LR, Boddy CN, Nomura CT
J Bacteriol 2013 May;195(9):2087-100
PubMed ID: 23457254
|
GcsR, a TyrR-Like Enhancer-Binding Protein, Regulates Expression of the Glycine Cleavage System in Pseudomonas aeruginosa PAO1.
Sarwar Z, Lundgren BR, Grassa MT, Wang MX, Gribble M, Moffat JF, Nomura CT
mSphere 2016 Mar-Apr;1(2)
PubMed ID: 27303730
|