Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2466
|
Name |
foxA
Synonym: foxA Synonym: optS |
Replicon | chromosome |
Genomic location | 2782764 - 2785226 (- strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 13 transposon mutants in orthologs |
RefSeq | NP_251156.1 |
GI | 15597662 |
Affymetrix | PA2466_at |
Entrez | 882859 |
GenBank | AAG05854.1 |
INSDC | AAG05854.1 |
NCBI Locus Tag | PA2466 |
protein_id(GenBank) | gb|AAG05854.1|AE004674_4|gnl|PseudoCAP|PA2466 |
TIGR | NTL03PA02466 |
UniParc | UPI00000C56EB |
UniProtKB Acc | Q9I116 |
UniProtKB ID | Q9I116_PSEAE |
UniRef100 | UniRef100_W0YQ97 |
UniRef50 | UniRef50_Q4KKG1 |
UniRef90 | UniRef90_B7V889 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Ferrioxamine receptor FoxA
|
Synonyms |
Ferrioxamine receptor FoxA |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -25.45 |
Kyte-Doolittle Hydrophobicity Value | -0.425 |
Molecular Weight (kDa) | 90.0 |
Isoelectric Point (pI) | 4.77 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
6I98 | MEMBRANE PROTEIN | 11/22/18 | Structure of the ferrioxamine B transporter FoxA from Pseudomonas aeruginosa, apo state | Pseudomonas aeruginosa | 2.8 | X-RAY DIFFRACTION | 100.0 |
6Z8A | MEMBRANE PROTEIN | 06/02/20 | Outer membrane FoxA in complex with nocardamine | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 2.95 | X-RAY DIFFRACTION | 100.0 |
8B43 | MEMBRANE PROTEIN | 09/19/22 | Crystal structure of ferrioxamine transporter | Pseudomonas aeruginosa | 2.49 | X-RAY DIFFRACTION | 100.0 |
6I96 | MEMBRANE PROTEIN | 11/22/18 | Structure of the ferrioxamine B transporter FoxA from Pseudomonas aeruginosa in complex with ferrioxamine B | Pseudomonas aeruginosa | 1.85 | X-RAY DIFFRACTION | 100.0 |
6I97 | MEMBRANE PROTEIN | 11/22/18 | Structure of the ferrioxamine B transporter FoxA from Pseudomonas aeruginosa in complex with ferrioxamine B and a C-terminal TonB fragment | Pseudomonas aeruginosa | 3.35 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 302 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000149 (2669 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2466
Search term: foxA
Search term: Ferrioxamine receptor FoxA
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Ferrioxamine uptake in Yersinia enterocolitica: characterization of the receptor protein FoxA.
Bäumler AJ, Hantke K
Mol Microbiol 1992 May;6(10):1309-21
PubMed ID: 1640832
|
The heterologous siderophores ferrioxamine B and ferrichrome activate signaling pathways in Pseudomonas aeruginosa.
Llamas MA, Sparrius M, Kloet R, Jiménez CR, Vandenbroucke-Grauls C, Bitter W
J Bacteriol 2006 Mar;188(5):1882-91
PubMed ID: 16484199
|