Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2527
|
Name |
muxB
Synonym: yegN |
Replicon | chromosome |
Genomic location | 2850883 - 2854014 (- strand) |
Transposon Mutants | 4 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 5 transposon mutants in orthologs |
RefSeq | NP_251217.1 |
GI | 15597723 |
Affymetrix | PA2527_at |
Entrez | 882889 |
GenBank | AAG05915.1 |
INSDC | AAG05915.1 |
NCBI Locus Tag | PA2527 |
protein_id(GenBank) | gb|AAG05915.1|AE004680_3|gnl|PseudoCAP|PA2527 |
TIGR | NTL03PA02527 |
UniParc | UPI00000C571E |
UniProtKB Acc | Q9I0V6 |
UniProtKB ID | Q9I0V6_PSEAE |
UniRef100 | UniRef100_A0A069QAI5 |
UniRef50 | UniRef50_Q1LR27 |
UniRef90 | UniRef90_W0WFC0 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
MuxB
|
Synonyms |
probable RND efflux transporter |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -13.06 |
Kyte-Doolittle Hydrophobicity Value | 0.355 |
Molecular Weight (kDa) | 112.3 |
Isoelectric Point (pI) | 5.07 |
Individual Mappings | |
Additional evidence for subcellular localization |
Identified using the Resistance Gene Identifier (RGI)
Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
MuxB | MuxB is one of the two necessary RND components in the Pseudomonas aeruginosa efflux pump system MuxABC-OpmB. [PMID:19713238] | ARO:3004074 | protein homolog model | Perfect | 1925.6 | 100.0 | 3.2.5 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 488 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001353 (1523 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2527
Search term: muxB
Search term: MuxB
|
Gene cloning and characteristics of the RND-type multidrug efflux pump MuxABC-OpmB possessing two RND components in Pseudomonas aeruginosa.
Mima T, Kohira N, Li Y, Sekiya H, Ogawa W, Kuroda T, Tsuchiya T
Microbiology (Reading) 2009 Nov;155(Pt 11):3509-3517
PubMed ID: 19713238
|