Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2614
|
Name |
lolA
|
Replicon | chromosome |
Genomic location | 2956153 - 2956779 (- strand) |
RefSeq | NP_251304.1 |
GI | 15597810 |
Affymetrix | PA2614_lolA_at |
DNASU | PaCD00007127 |
Entrez | 882320 |
GenBank | AAG06002.1 |
INSDC | AAG06002.1 |
NCBI Locus Tag | PA2614 |
protein_id(GenBank) | gb|AAG06002.1|AE004690_2|gnl|PseudoCAP|PA2614 |
TIGR | NTL03PA02614 |
UniParc | UPI000012E7B5 |
UniProtKB Acc | Q9I0M4 |
UniProtKB ID | LOLA_PSEAE |
UniRef100 | UniRef100_B7UW08 |
UniRef50 | UniRef50_Q4K9V4 |
UniRef90 | UniRef90_B7UW08 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
lipoprotein localization protein LolA
|
Synonyms |
periplasmic chaperone LolA |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
Detected by two-dimensional gel electrophoresis and mass spectral analysis(PMID:21863142).
|
Charge (pH 7) | -1.52 |
Kyte-Doolittle Hydrophobicity Value | -0.154 |
Molecular Weight (kDa) | 23.1 |
Isoelectric Point (pI) | 5.83 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
2W7Q | PROTEIN TRANSPORT | 12/23/08 | Structure of Pseudomonas aeruginosa LolA | PSEUDOMONAS AERUGINOSA | 1.88 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 204 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002937 (536 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2614
Search term: lolA
Search term: lipoprotein localization protein LolA
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Genetic analyses of the in vivo function of LolA, a periplasmic chaperone involved in the outer membrane localization of Escherichia coli lipoproteins.
Tajima T, Yokota N, Matsuyama S, Tokuda H
FEBS Lett 1998 Nov 13;439(1-2):51-4
PubMed ID: 9849875
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.
Rao J, Damron FH, Basler M, Digiandomenico A, Sherman NE, Fox JW, Mekalanos JJ, Goldberg JB
Front Microbiol 2011;2:162
PubMed ID: 21863142
|
Characterization of the Pseudomonas aeruginosa Lol system as a lipoprotein sorting mechanism.
Tanaka SY, Narita S, Tokuda H
J Biol Chem 2007 May 4;282(18):13379-84
PubMed ID: 17350955
|