Pseudomonas aeruginosa PAO1, PA2621 (clpS)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
| Locus Tag |
PA2621
|
| Name |
clpS
|
| Replicon | chromosome |
| Genomic location | 2964607 - 2964843 (- strand) |
| Transposon Mutants | 2 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_251311 |
| GI | 161486763 |
| Affymetrix | PA2621_at |
| DNASU | PaCD00007131 |
| Entrez | 882327 |
| GenBank | AAG06009.1 |
| NCBI Locus Tag | PA2621 |
| protein_id(GenBank) | gb|AAG06009.1|AE004690_9|gnl|PseudoCAP|PA2621 |
| TIGR | NTL03PA02621 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
ClpS
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -4.59 |
| Kyte-Doolittle Hydrophobicity Value | -0.159 |
| Molecular Weight (kDa) | 9.0 |
| Isoelectric Point (pI) | 4.55 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 255 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG002931 (535 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA2621
Search term: clpS
Search term: ClpS
|
Human Homologs
References
|
Role of intracellular proteases in the antibiotic resistance, motility, and biofilm formation of Pseudomonas aeruginosa.
Fernández L, Breidenstein EB, Song D, Hancock RE
Antimicrob Agents Chemother 2012 Feb;56(2):1128-32
PubMed ID: 22123702
|