Pseudomonas aeruginosa PAO1, PA2694 (trx2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2694
Name
trx2
Replicon chromosome
Genomic location 3047644 - 3047970 (- strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251384.1
GI 15597890
Affymetrix PA2694_at
DNASU PaCD00007162
Entrez 882710
GenBank AAG06082.1
INSDC AAG06082.1
NCBI Locus Tag PA2694
protein_id(GenBank) gb|AAG06082.1|AE004697_7|gnl|PseudoCAP|PA2694
TIGR NTL03PA02694
UniParc UPI00000C57B2
UniProtKB Acc Q9I0E8
UniProtKB ID Q9I0E8_PSEAE
UniRef100 UniRef100_W0YS02
UniRef50 UniRef50_A0A077JV72
UniRef90 UniRef90_A0A077JV72

Product

Feature Type CDS
Coding Frame 1
Product Name
Trx2
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.59
Kyte-Doolittle Hydrophobicity Value -0.287
Molecular Weight (kDa) 11.9
Isoelectric Point (pI) 4.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2LRC OXIDOREDUCTASE 03/28/12 Structure of thioredoxin 2 from Pseudomonas aeruginosa PAO1 in its reduced form Pseudomonas aeruginosa NOT SOLUTION NMR 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 361 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002868 (336 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2694
Search term: trx2
Search term: Trx2

Human Homologs

References

¹H, ¹³C and ¹⁵N backbone and side-chain chemical shift assignments for reduced unusual thioredoxin Patrx2 of Pseudomonas aeruginosa.
Garcin EB, Bornet O, Elantak L, Nouailler M, Guerlesquin F, Sebban-Kreuzer C
Biomol NMR Assign 2014 Oct;8(2):247-50
PubMed ID: 23771858