Pseudomonas aeruginosa PAO1, PA2780 (bswR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2780
Name
bswR
Replicon chromosome
Genomic location 3137850 - 3138194 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251470.1
GI 15597976
Affymetrix PA2780_at
DNASU PaCD00007208
Entrez 882763
GenBank AAG06168.1
INSDC AAG06168.1
NCBI Locus Tag PA2780
protein_id(GenBank) gb|AAG06168.1|AE004705_10|gnl|PseudoCAP|PA2780
TIGR NTL03PA02780
UniParc UPI00000C5800
UniProtKB Acc Q9I063
UniProtKB ID Q9I063_PSEAE
UniRef100 UniRef100_W0YVH0
UniRef50 UniRef50_A6V434
UniRef90 UniRef90_A6V434

Product

Feature Type CDS
Coding Frame 1
Product Name
bacterial swarming regulator BswR
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 3.20
Kyte-Doolittle Hydrophobicity Value -0.407
Molecular Weight (kDa) 13.0
Isoelectric Point (pI) 9.56

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4O8B DNA BINDING PROTEIN 12/26/13 Crystal structure of transcriptional regulator BswR Pseudomonas aeruginosa 2.3 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 36 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002789 (303 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2780
Search term: bswR

Human Homologs

References

BswR controls bacterial motility and biofilm formation in Pseudomonas aeruginosa through modulation of the small RNA rsmZ.
Wang C, Ye F, Kumar V, Gao YG, Zhang LH
Nucleic Acids Res 2014 Apr;42(7):4563-76
PubMed ID: 24497189