Pseudomonas aeruginosa PAO1, PA2891 (atuF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2891
Name
atuF
Replicon chromosome
Genomic location 3244345 - 3246330 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251581.1
GI 15598087
Affymetrix PA2891_at
Entrez 882709
GenBank AAG06279.1
INSDC AAG06279.1
NCBI Locus Tag PA2891
protein_id(GenBank) gb|AAG06279.1|AE004715_5|gnl|PseudoCAP|PA2891
TIGR NTL03PA02891
UniParc UPI00000C5866
UniProtKB Acc Q9HZV6
UniProtKB ID Q9HZV6_PSEAE
UniRef100 UniRef100_Q9HZV6
UniRef50 UniRef50_Q4K8Z2
UniRef90 UniRef90_W0WFC7

Product

Feature Type CDS
Coding Frame 1
Product Name
geranyl-CoA carboxylase, alpha-subunit (biotin-containing)
Product Name Confidence: Class 1
Synonyms gamma-carboxygeranyl-CoA hydratase
Evidence for Translation
Charge (pH 7) -9.62
Kyte-Doolittle Hydrophobicity Value -0.115
Molecular Weight (kDa) 71.7
Isoelectric Point (pI) 6.13

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 633 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002682 (404 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2891
Search term: atuF

Human Homologs

Ensembl 110, assembly GRCh38.p14
methylcrotonyl-CoA carboxylase subunit 1 [Source:HGNC Symbol;Acc:HGNC:6936]
E-value: 1.6e-143
Percent Identity: 44.4

References

Identification of genes and proteins necessary for catabolism of acyclic terpenes and leucine/isovalerate in Pseudomonas aeruginosa.
Förster-Fromme K, Höschle B, Mack C, Bott M, Armbruster W, Jendrossek D
Appl Environ Microbiol 2006 Jul;72(7):4819-28
PubMed ID: 16820476