Pseudomonas aeruginosa PAO1, PA2896 (sbrI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2896
Name
sbrI
Replicon chromosome
Genomic location 3250738 - 3251322 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251586.1
GI 15598092
Affymetrix PA2896_at
Entrez 882789
GenBank AAG06284.1
INSDC AAG06284.1
NCBI Locus Tag PA2896
protein_id(GenBank) gb|AAG06284.1|AE004716_2|gnl|PseudoCAP|PA2896
TIGR NTL03PA02896
UniParc UPI00000C586B
UniProtKB Acc Q9HZV1
UniProtKB ID Q9HZV1_PSEAE
UniRef100 UniRef100_W0YSR6
UniRef50 UniRef50_Q4KKB3
UniRef90 UniRef90_A6V3J5

Product

Feature Type CDS
Coding Frame 1
Product Name
SbrI
Product Name Confidence: Class 1
Synonyms probable sigma-70 factor, ECF subfamily
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.59
Kyte-Doolittle Hydrophobicity Value -0.676
Molecular Weight (kDa) 22.3
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 482 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001286 (856 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2896
Search term: sbrI
Search term: SbrI

Human Homologs

References

σ Factor and Anti-σ Factor That Control Swarming Motility and Biofilm Formation in Pseudomonas aeruginosa.
McGuffie BA, Vallet-Gely I, Dove SL
J. Bacteriol. 2015 Nov;198(5):755-65
PubMed ID: 26620262