Pseudomonas aeruginosa PAO1, PA2948 (cobM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2948
Name
cobM
Synonym: cbiF
Replicon chromosome
Genomic location 3307510 - 3308262 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251638.1
GI 15598144
Affymetrix PA2948_cobM_at
Entrez 882854
GenBank AAG06336.1
INSDC AAG06336.1
NCBI Locus Tag PA2948
protein_id(GenBank) gb|AAG06336.1|AE004721_4|gnl|PseudoCAP|PA2948
TIGR NTL03PA02948
UniParc UPI00000C589F
UniProtKB Acc Q9HZP9
UniProtKB ID COBM_PSEAE
UniRef100 UniRef100_Q9HZP9
UniRef50 UniRef50_Q53138
UniRef90 UniRef90_Q9HZP9

Product

Feature Type CDS
Coding Frame 1
Product Name
precorrin-3 methylase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -2.48
Kyte-Doolittle Hydrophobicity Value 0.085
Molecular Weight (kDa) 27.0
Isoelectric Point (pI) 6.58

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 536 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002632 (505 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2948
Search term: cobM

Human Homologs

References

Genetic and sequence analysis of an 8.7-kilobase Pseudomonas denitrificans fragment carrying eight genes involved in transformation of precorrin-2 to cobyrinic acid.
Crouzet J, Cameron B, Cauchois L, Rigault S, Rouyez MC, Blanche F, Thibaut D, Debussche L
J Bacteriol 1990 Oct;172(10):5980-90
PubMed ID: 2211521