Pseudomonas aeruginosa PAO1, PA2986 (lolC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA2986
Name
lolC
Replicon chromosome
Genomic location 3343799 - 3345100 (- strand)

Cross-References

RefSeq NP_251676.1
GI 15598182
Affymetrix PA2986_at
Entrez 880596
GenBank AAG06374.1
INSDC AAG06374.1
NCBI Locus Tag PA2986
protein_id(GenBank) gb|AAG06374.1|AE004724_3|gnl|PseudoCAP|PA2986
TIGR NTL03PA02986
UniParc UPI00000C58B7
UniProtKB Acc Q9HZL8
UniProtKB ID Q9HZL8_PSEAE
UniRef100 UniRef100_Q9HZL8
UniRef50 UniRef50_Q9HZL8
UniRef90 UniRef90_Q9HZL8

Product

Feature Type CDS
Coding Frame 1
Product Name
lipoprotein localization protein LolC
Product Name Confidence: Class 1
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 11.38
Kyte-Doolittle Hydrophobicity Value 0.370
Molecular Weight (kDa) 47.4
Isoelectric Point (pI) 10.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 506 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002596 (556 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2986
Search term: lolC

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
Characterization of the Pseudomonas aeruginosa Lol system as a lipoprotein sorting mechanism.
Tanaka SY, Narita S, Tokuda H
J. Biol. Chem. 2007 May;282(18):13379-84
PubMed ID: 17350955