Pseudomonas aeruginosa PAO1, PA2988 (lolE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA2988
Name
lolE
Replicon chromosome
Genomic location 3345789 - 3347039 (- strand)

Cross-References

RefSeq NP_251678.1
GI 15598184
Affymetrix PA2988_at
Entrez 880587
GenBank AAG06376.1
INSDC AAG06376.1
NCBI Locus Tag PA2988
protein_id(GenBank) gb|AAG06376.1|AE004724_5|gnl|PseudoCAP|PA2988
TIGR NTL03PA02988
UniParc UPI00000C58B9
UniProtKB Acc Q9HZL6
UniProtKB ID Q9HZL6_PSEAE
UniRef100 UniRef100_Q9HZL6
UniRef50 UniRef50_Q9HZL8
UniRef90 UniRef90_Q9HZL6

Product

Feature Type CDS
Coding Frame 1
Product Name
lipoprotein localization protein LolE
Product Name Confidence: Class 1
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 5.41
Kyte-Doolittle Hydrophobicity Value 0.455
Molecular Weight (kDa) 45.4
Isoelectric Point (pI) 9.47

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 531 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002594 (559 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2988
Search term: lolE

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
Characterization of the Pseudomonas aeruginosa Lol system as a lipoprotein sorting mechanism.
Tanaka SY, Narita S, Tokuda H
J. Biol. Chem. 2007 May;282(18):13379-84
PubMed ID: 17350955