Pseudomonas aeruginosa PAO1, PA3038 (opdQ)

Cytoplasmic Membrane
Outer Membrane
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
Synonym: OccK6
Replicon chromosome
Genomic location 3400684 - 3401949 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs


RefSeq NP_251728.1
GI 15598234
Affymetrix PA3038_at
Entrez 882877
GenBank AAG06426.1
INSDC AAG06426.1
NCBI Locus Tag PA3038
protein_id(GenBank) gb|AAG06426.1|AE004728_12|gnl|PseudoCAP|PA3038
UniParc UPI00000C58DF
UniProtKB Acc Q9HZH0
UniRef100 UniRef100_A0A069QDK5
UniRef50 UniRef50_W6QYC2
UniRef90 UniRef90_A0A069QDK5


Feature Type CDS
Coding Frame 1
Product Name
Product Name Confidence: Class 1
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
Charge (pH 7) 0.20
Kyte-Doolittle Hydrophobicity Value -0.469
Molecular Weight (kDa) 46.7
Isoelectric Point (pI) 7.09

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3T24 MEMBRANE PROTEIN 07/22/11 Crystal structure of Pseudomonas aeruginosa OpdQ PSEUDOMONAS AERUGINOSA 2.4 X-RAY DIFFRACTION 99.5

Pathogen Association Analysis

Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 25 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002549 (381 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: PA3038
Search term: opdQ
Search term: OpdQ

Transposon Insertions in PAO1

Type ISphoA/hah insertion site
Mutant ID UWGC: 32047
Genomic Position 3400941
Position in ORF 258(1266)
Reference 14617778
Type ISphoA/hah insertion site
Mutant ID UWGC: 32500
Genomic Position 3400956
Position in ORF 273(1266)
Reference 14617778

Transposon Insertions in Orthologs

Type MAR2xT7 transposon (wild type background) insertion site
Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag PA14_24790
Mutant ID PA14NR: 48754
Genomic Position 2168468
Position in ORF 1061(1266)
Reference 16477005


Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM.
Proteomics. 2009 Apr;9(7):1901-15.
PubMed ID: 19333994
The OpdQ porin of Pseudomonas aeruginosa is regulated by environmental signals associated with cystic fibrosis including nitrate-induced regulation involving the NarXL two-component system.
Fowler RC(1), Hanson ND(1).
Microbiologyopen. 2015 Dec;4(6):967-982.
PubMed ID: 26459101
OccK channels from Pseudomonas aeruginosa exhibit diverse single-channel electrical signatures but conserved anion selectivity.
Liu J(1), Eren E, Vijayaraghavan J, Cheneke BR, Indic M, van den Berg B, Movileanu L.
Biochemistry. 2012 Mar 20;51(11):2319-30.
PubMed ID: 22369314