Pseudomonas aeruginosa PAO1, PA3061 (pelD)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PAO1 (Stover et al., 2000) GCF_000006765.1|latest
Locus Tag	PA3061
Name	pelD
Replicon	chromosome
Genomic location	3425555 - 3426922 (- strand)
Transposon Mutants	4 transposon mutants in PAO1
Transposon Mutants in orthologs	1 transposon mutants in orthologs

Cross-References

RefSeq	NP_251751.1
GI	15598257
Affymetrix	PA3061_at
Entrez	880405
GenBank	AAG06449.1
INSDC	AAG06449.1
NCBI Locus Tag	PA3061
protein_id(GenBank)	gb|AAG06449.1|AE004730_13|gnl|PseudoCAP|PA3061
TIGR	NTL03PA03061
UniParc	UPI00000C58F5
UniProtKB Acc	Q9HZE7
UniProtKB ID	Q9HZE7_PSEAE
UniRef100	UniRef100_Q9HZE7
UniRef50	UniRef50_Q02PM6
UniRef90	UniRef90_Q02PM6

Product

Feature Type	CDS
Coding Frame	1
Product Name	PelD Product Name Confidence: Class 1
Synonyms	PelD
Evidence for Translation
Charge (pH 7)	-7.20
Kyte-Doolittle Hydrophobicity Value	0.029
Molecular Weight (kDa)	51.1
Isoelectric Point (pI)	5.53

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4EUV	SIGNALING PROTEIN	04/25/12	Crystal Structure of PelD 158-CT from Pseudomonas aeruginosa PAO1, in complex with c-di-GMP, form 1	Pseudomonas aeruginosa	2	X-RAY DIFFRACTION	99.3
4DN0	Nucleotide-binding Protein	02/08/12	PelD 156-455 from Pseudomonas aeruginosa PA14 in complex with c-di-GMP	Pseudomonas aeruginosa	2.3	X-RAY DIFFRACTION	99.0
4ETX	SIGNALING PROTEIN	04/24/12	Crystal Structure of PelD 158-CT from Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa	2	X-RAY DIFFRACTION	100.0
4ETZ	SIGNALING PROTEIN	04/24/12	Crystal Structure of PelD 158-CT from Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa	2.05	X-RAY DIFFRACTION	100.0
4EU0	SIGNALING PROTEIN	04/24/12	Crystal Structure of PelD 158-CT from Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa	1.7	X-RAY DIFFRACTION	99.3
4DMZ	Nucleotide-binding Protein	02/08/12	PelD 156-455 from Pseudomonas aeruginosa PA14, apo form	Pseudomonas aeruginosa	2.102	X-RAY DIFFRACTION	99.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 24 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002528 (344 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA3061 Search term: pelD Search term: PelD

Human Homologs

References

Genes involved in matrix formation in Pseudomonas aeruginosa PA14 biofilms. Friedman L, Kolter R Mol Microbiol 2004 Feb;51(3):675-90 PubMed ID: 14731271

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen. Lewenza S, Gardy JL, Brinkman FS, Hancock RE Genome Res 2005 Feb;15(2):321-9 PubMed ID: 15687295

The pel genes of the Pseudomonas aeruginosa PAK strain are involved at early and late stages of biofilm formation. Vasseur P, Vallet-Gely I, Soscia C, Genin S, Filloux A Microbiology (Reading) 2005 Mar;151(Pt 3):985-997 PubMed ID: 15758243

A cyclic-di-GMP receptor required for bacterial exopolysaccharide production. Lee VT, Matewish JM, Kessler JL, Hyodo M, Hayakawa Y, Lory S Mol Microbiol 2007 Sep;65(6):1474-84 PubMed ID: 17824927