Pseudomonas aeruginosa PAO1, PA3062 (pelC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3062
Name
pelC
Replicon chromosome
Genomic location 3426928 - 3427446 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_251752.1
GI 15598258
Affymetrix PA3062_at
Entrez 880406
GenBank AAG06450.1
INSDC AAG06450.1
NCBI Locus Tag PA3062
protein_id(GenBank) gb|AAG06450.1|AE004730_14|gnl|PseudoCAP|PA3062
TIGR NTL03PA03062
UniParc UPI00000C58F6
UniProtKB Acc Q9HZE6
UniProtKB ID Q9HZE6_PSEAE
UniRef100 UniRef100_W0YT75
UniRef50 UniRef50_Q4KCF3
UniRef90 UniRef90_W0YT75

Product

Feature Type CDS
Coding Frame 1
Product Name
PelC
Product Name Confidence: Class 1
Synonyms PelC
Evidence for Translation
Charge (pH 7) -2.07
Kyte-Doolittle Hydrophobicity Value -0.165
Molecular Weight (kDa) 18.7
Isoelectric Point (pI) 4.98

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 26 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002527 (344 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3062
Search term: pelC
Search term: PelC

Human Homologs

References

Two genetic loci produce distinct carbohydrate-rich structural components of the Pseudomonas aeruginosa biofilm matrix.
Friedman L, Kolter R
J Bacteriol 2004 Jul;186(14):4457-65
PubMed ID: 15231777
The pel genes of the Pseudomonas aeruginosa PAK strain are involved at early and late stages of biofilm formation.
Vasseur P, Vallet-Gely I, Soscia C, Genin S, Filloux A
Microbiology (Reading) 2005 Mar;151(Pt 3):985-997
PubMed ID: 15758243
PelC is a Pseudomonas aeruginosa outer membrane lipoprotein of the OMA family of proteins involved in exopolysaccharide transport.
Vasseur P, Soscia C, Voulhoux R, Filloux A
Biochimie 2007 Aug;89(8):903-15
PubMed ID: 17524545