Pseudomonas aeruginosa PAO1, PA3092 (fadH1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3092
Name
fadH1
Replicon chromosome
Genomic location 3470764 - 3472803 (- strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_251782.1
GI 15598288
Affymetrix PA3092_fadH1_at
Entrez 879829
GenBank AAG06480.1
INSDC AAG06480.1
NCBI Locus Tag PA3092
protein_id(GenBank) gb|AAG06480.1|AE004733_7|gnl|PseudoCAP|PA3092
TIGR NTL03PA03092
UniParc UPI00000C5912
UniProtKB Acc Q9HZB6
UniProtKB ID Q9HZB6_PSEAE
UniRef100 UniRef100_Q9HZB6
UniRef50 UniRef50_W5YMG5
UniRef90 UniRef90_Q9HZB6

Product

Feature Type CDS
Coding Frame 1
Product Name
2,4-dienoyl-CoA reductase FadH1
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.37
Kyte-Doolittle Hydrophobicity Value -0.104
Molecular Weight (kDa) 73.0
Isoelectric Point (pI) 7.17

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 565 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002500 (829 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3092
Search term: fadH1

Human Homologs

References

Cloning and expression of the fadH gene and characterization of the gene product 2,4-dienoyl coenzyme A reductase from Escherichia coli.
He XY, Yang SY, Schulz H
Eur J Biochem 1997 Sep 1;248(2):516-20
PubMed ID: 9346310