Pseudomonas aeruginosa PAO1, PA3095 (xcpZ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3095
Name
xcpZ
Replicon chromosome
Genomic location 3475956 - 3476480 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251785.1
GI 15598291
Affymetrix PA3095_xcpZ_at
DNASU PaCD00007361
Entrez 882766
GenBank AAG06483.1
INSDC AAG06483.1
NCBI Locus Tag PA3095
protein_id(GenBank) gb|AAG06483.1|AE004734_1|gnl|PseudoCAP|PA3095
TIGR NTL03PA03095
UniParc UPI000012BC72
UniProtKB Acc P25061
UniProtKB ID GSPM_PSEAE
UniRef100 UniRef100_P25061
UniRef50 UniRef50_P25061
UniRef90 UniRef90_P25061

Product

Feature Type CDS
Coding Frame 1
Product Name
general secretion pathway protein M
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 2.71
Kyte-Doolittle Hydrophobicity Value -0.115
Molecular Weight (kDa) 19.3
Isoelectric Point (pI) 9.73

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 26 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002497 (329 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3095
Search term: xcpZ

Human Homologs

References

Subcomplexes from the Xcp secretion system of Pseudomonas aeruginosa.
Robert V, Filloux A, Michel GP
FEMS Microbiol Lett 2005 Nov 1;252(1):43-50
PubMed ID: 16168578
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Protein secretion in gram-negative bacteria: transport across the outer membrane involves common mechanisms in different bacteria.
Filloux A, Bally M, Ball G, Akrim M, Tommassen J, Lazdunski A
EMBO J 1990 Dec;9(13):4323-9
PubMed ID: 2124971