Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3153
|
Name |
wzx
Synonym: wbpF Synonym: rfbX |
Replicon | chromosome |
Genomic location | 3536576 - 3537811 (- strand) |
RefSeq | NP_251843.1 |
GI | 15598349 |
Affymetrix | PA3153_wzx_at |
Entrez | 882590 |
GenBank | AAG06541.1 |
INSDC | AAG06541.1 |
NCBI Locus Tag | PA3153 |
protein_id(GenBank) | gb|AAG06541.1|AE004739_3|gnl|PseudoCAP|PA3153 |
TIGR | NTL03PA03153 |
UniParc | UPI00000DA0EF |
UniProtKB Acc | G3XD19 |
UniProtKB ID | G3XD19_PSEAE |
UniRef100 | UniRef100_G3XD19 |
UniRef50 | UniRef50_G3XD19 |
UniRef90 | UniRef90_G3XD19 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
O-antigen translocase
|
Synonyms |
O-antigen flippase |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 5.07 |
Kyte-Doolittle Hydrophobicity Value | 0.968 |
Molecular Weight (kDa) | 45.3 |
Isoelectric Point (pI) | 8.85 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | VFDB : VF0085 |
Category | LPS O-antigen (P. aeruginosa) |
Evidence |
|
Host Organism | |
Notes | |
Reference |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 76 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG005137 (38 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3153
Search term: wzx
Search term: O-antigen translocase
|
An O-antigen processing function for Wzx (RfbX): a promising candidate for O-unit flippase.
Liu D, Cole RA, Reeves PR
J Bacteriol 1996 Apr;178(7):2102-7
PubMed ID: 8606190
|
Effect of wzx (rfbX) mutations on A-band and B-band lipopolysaccharide biosynthesis in Pseudomonas aeruginosa O5.
Burrows LL, Lam JS
J Bacteriol 1999 Feb;181(3):973-80
PubMed ID: 9922263
|
A cationic lumen in the Wzx flippase mediates anionic O-antigen subunit translocation in Pseudomonas aeruginosa PAO1.
Islam ST, Fieldhouse RJ, Anderson EM, Taylor VL, Keates RA, Ford RC, Lam JS
Mol Microbiol 2012 Jun;84(6):1165-76
PubMed ID: 22554073
|
A cationic lumen in the Wzx flippase mediates anionic O-antigen subunit translocation in Pseudomonas aeruginosa PAO1.
Islam ST, Fieldhouse RJ, Anderson EM, Taylor VL, Keates RA, Ford RC, Lam JS
Mol Microbiol 2012 Jun;84(6):1165-76
PubMed ID: 22554073
|