Pseudomonas aeruginosa PAO1, PA3163 (cmk)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA3163
Name
cmk
Replicon chromosome
Genomic location 3550057 - 3550746 (- strand)

Cross-References

RefSeq NP_251853.1
GI 15598359
Affymetrix PA3163_cmk_at
Entrez 878958
GenBank AAG06551.1
INSDC AAG06551.1
NCBI Locus Tag PA3163
protein_id(GenBank) gb|AAG06551.1|AE004740_4|gnl|PseudoCAP|PA3163
TIGR NTL03PA03163
UniParc UPI000012DCF7
UniProtKB Acc Q9HZ70
UniProtKB ID KCY_PSEAE
UniRef100 UniRef100_Q02PW9
UniRef50 UniRef50_Q9KQT2
UniRef90 UniRef90_Q02PW9

Product

Feature Type CDS
Coding Frame 1
Product Name
cytidylate kinase
Product Name Confidence: Class 2
Synonyms cytidine monophosphate kinase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -8.06
Kyte-Doolittle Hydrophobicity Value -0.072
Molecular Weight (kDa) 24.6
Isoelectric Point (pI) 4.78

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 567 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002452 (561 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3163
Search term: cmk
Search term: cytidylate kinase

References

The cmk gene encoding cytidine monophosphate kinase is located in the rpsA operon and is required for normal replication rate in Escherichia coli.
Fricke J, Neuhard J, Kelln RA, Pedersen S
J. Bacteriol. 1995 Feb;177(3):517-23
PubMed ID: 7836281
A probable mixed-function supraoperon in Pseudomonas exhibits gene organization features of both intergenomic conservation and gene shuffling.
Xie G, Bonner CA, Jensen RA
J. Mol. Evol. 1999 Jul;49(1):108-21
PubMed ID: 10368439