Pseudomonas aeruginosa PAO1, PA3168 (gyrA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA3168
Name
gyrA
Replicon chromosome
Genomic location 3556427 - 3559198 (- strand)

Cross-References

RefSeq NP_251858.1
GI 15598364
Affymetrix PA3168_gyrA_at
Entrez 882800
GenBank AAG06556.1
INSDC AAG06556.1
NCBI Locus Tag PA3168
protein_id(GenBank) gb|AAG06556.1|AE004741_1|gnl|PseudoCAP|PA3168
TIGR NTL03PA03168
UniParc UPI000012BE96
UniProtKB Acc P48372
UniProtKB ID GYRA_PSEAE
UniRef100 UniRef100_P48372
UniRef50 UniRef50_P0AES4
UniRef90 UniRef90_P48372

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA gyrase subunit A
Product Name Confidence: Class 1
Synonyms DNA topoisomerase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -40.06
Kyte-Doolittle Hydrophobicity Value -0.248
Molecular Weight (kDa) 101.1
Isoelectric Point (pI) 4.62

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 631 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002447 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3168
Search term: gyrA

References

Cloning and nucleotide sequence of Pseudomonas aeruginosa DNA gyrase gyrA gene from strain PAO1 and quinolone-resistant clinical isolates.
Kureishi A, Diver JM, Beckthold B, Schollaardt T, Bryan LE
Antimicrob. Agents Chemother. 1994 Sep;38(9):1944-52
PubMed ID: 7811002