Pseudomonas aeruginosa PAO1, PA3173

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3173
Name
Synonym: yciK
Replicon chromosome
Genomic location 3563546 - 3564286 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251863.1
GI 15598369
Affymetrix PA3173_at
Entrez 882633
GenBank AAG06561.1
INSDC AAG06561.1
NCBI Locus Tag PA3173
protein_id(GenBank) gb|AAG06561.1|AE004741_6|gnl|PseudoCAP|PA3173
TIGR NTL03PA03173
UniParc UPI00000C5935
UniProtKB Acc Q9HZ61
UniProtKB ID Q9HZ61_PSEAE
UniRef100 UniRef100_Q9HZ61
UniRef50 UniRef50_G2FE54
UniRef90 UniRef90_A0A072ZRY7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable short-chain dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -6.80
Kyte-Doolittle Hydrophobicity Value -0.031
Molecular Weight (kDa) 26.3
Isoelectric Point (pI) 4.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database Victors : 4269
Category
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Rattus norvegicus
Notes
Infection model Rat agar bead model of chronic lung infection
Reference 14641575

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 646 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002442 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3173

Human Homologs

Ensembl 110, assembly GRCh38.p14
hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213]
E-value: 1.1e-12
Percent Identity: 31.7
Ensembl 110, assembly GRCh38.p14
hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213]
E-value: 1.1e-12
Percent Identity: 31.7
Ensembl 110, assembly GRCh38.p14
hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213]
E-value: 1.1e-12
Percent Identity: 31.7
Ensembl 110, assembly GRCh38.p14
hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213]
E-value: 1.1e-12
Percent Identity: 31.7
Ensembl 110, assembly GRCh38.p14
hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213]
E-value: 1.1e-12
Percent Identity: 31.7
Ensembl 110, assembly GRCh38.p14
hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213]
E-value: 1.1e-12
Percent Identity: 31.7

References

No references are associated with this feature.