Pseudomonas aeruginosa PAO1, PA3174 (hutR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3174
Name
hutR
Replicon chromosome
Genomic location 3564445 - 3565173 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251864.1
GI 15598370
Affymetrix PA3174_at
DNASU PaCD00007398
Entrez 882684
GenBank AAG06562.1
INSDC AAG06562.1
NCBI Locus Tag PA3174
protein_id(GenBank) gb|AAG06562.1|AE004741_7|gnl|PseudoCAP|PA3174
TIGR NTL03PA03174
UniParc UPI00000C5936
UniProtKB Acc Q9HZ60
UniProtKB ID Q9HZ60_PSEAE
UniRef100 UniRef100_Q9HZ60
UniRef50 UniRef50_Q4KJU0
UniRef90 UniRef90_Q9HZ60

Product

Feature Type CDS
Coding Frame 1
Product Name
HutR
Product Name Confidence: Class 1
Synonyms probable transcriptional regulator
Evidence for Translation
Charge (pH 7) 0.05
Kyte-Doolittle Hydrophobicity Value -0.223
Molecular Weight (kDa) 26.8
Isoelectric Point (pI) 7.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 296 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002441 (346 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3174
Search term: hutR
Search term: HutR

Human Homologs

References

The origin and ecological significance of multiple branches for histidine utilization in Pseudomonas aeruginosa PAO1.
Gerth ML, Ferla MP, Rainey PB
Environ Microbiol 2012 Aug;14(8):1929-40
PubMed ID: 22225844