Pseudomonas aeruginosa PAO1, PA3176 (gltS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA3176
Name
gltS
Replicon chromosome
Genomic location 3566163 - 3567377 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251866.1
GI 15598372
Affymetrix PA3176_gltS_at
Entrez 882660
GenBank AAG06564.1
INSDC AAG06564.1
NCBI Locus Tag PA3176
protein_id(GenBank) gb|AAG06564.1|AE004741_9|gnl|PseudoCAP|PA3176
TIGR NTL03PA03176
UniParc UPI00000C5938
UniProtKB Acc Q9HZ58
UniProtKB ID Q9HZ58_PSEAE
UniRef100 UniRef100_Q9HZ58
UniRef50 UniRef50_Q9HZ58
UniRef90 UniRef90_Q9HZ58

Product

Feature Type CDS
Coding Frame 1
Product Name
glutamate/sodium ion symporter, GltS
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 2.22
Kyte-Doolittle Hydrophobicity Value 0.857
Molecular Weight (kDa) 42.8
Isoelectric Point (pI) 7.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 118 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002439 (395 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3176
Search term: gltS

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
Nucleotide sequence of gltS, the Na+/glutamate symport carrier gene of Escherichia coli B.
Deguchi Y, Yamato I, Anraku Y
J. Biol. Chem. 1990 Dec;265(35):21704-8
PubMed ID: 2254324
High-throughput phenotypic characterization of Pseudomonas aeruginosa membrane transport genes.
Johnson DA, Tetu SG, Phillippy K, Chen J, Ren Q, Paulsen IT
PLoS Genet. 2008 Oct;4(10):e1000211
PubMed ID: 18833300