Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3257
|
Name |
algO
Synonym: tsp Synonym: prc |
Replicon | chromosome |
Genomic location | 3642931 - 3645060 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_251947.1 |
GI | 15598453 |
Affymetrix | PA3257_prc_at |
Entrez | 882420 |
GenBank | AAG06645.1 |
INSDC | AAG06645.1 |
NCBI Locus Tag | PA3257 |
protein_id(GenBank) | gb|AAG06645.1|AE004748_3|gnl|PseudoCAP|PA3257 |
TIGR | NTL03PA03257 |
UniParc | UPI00000C597A |
UniProtKB Acc | Q9HYY3 |
UniProtKB ID | Q9HYY3_PSEAE |
UniRef100 | UniRef100_Q9HYY3 |
UniRef50 | UniRef50_Q4K8E7 |
UniRef90 | UniRef90_Q9HYY3 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
AlgO
|
Synonyms |
periplasmic tail-specific protease |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -2.31 |
Kyte-Doolittle Hydrophobicity Value | -0.503 |
Molecular Weight (kDa) | 78.2 |
Isoelectric Point (pI) | 6.61 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 505 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002353 (535 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3257
Search term: algO
Search term: AlgO
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Cloning, mapping, and characterization of the Escherichia coli prc gene, which is involved in C-terminal processing of penicillin-binding protein 3.
Hara H, Yamamoto Y, Higashitani A, Suzuki H, Nishimura Y
J Bacteriol 1991 Aug;173(15):4799-813
PubMed ID: 1856173
|
Tsp: a tail-specific protease that selectively degrades proteins with nonpolar C termini.
Silber KR, Keiler KC, Sauer RT
Proc Natl Acad Sci U S A 1992 Jan 1;89(1):295-9
PubMed ID: 1729701
|
Multiple antibiotic susceptibility associated with inactivation of the prc gene.
Seoane A, Sabbaj A, McMurry LM, Levy SB
J Bacteriol 1992 Dec;174(23):7844-7
PubMed ID: 1447154
|
Evidence for PDZ domains in bacteria, yeast, and plants.
Ponting CP
Protein Sci 1997 Feb;6(2):464-8
PubMed ID: 9041651
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and algT/U activity results in the loss of alginate production.
Sautter R, Ramos D, Schneper L, Ciofu O, Wassermann T, Koh CL, Heydorn A, Hentzer M, Høiby N, Kharazmi A, Molin S, Devries CA, Ohman DE, Mathee K
Gene 2012 May 1;498(2):242-53
PubMed ID: 22088575
|
Prc protease promotes mucoidy in mucA mutants of Pseudomonas aeruginosa.
Reiling SA, Jansen JA, Henley BJ, Singh S, Chattin C, Chandler M, Rowen DW
Microbiology (Reading) 2005 Jul;151(Pt 7):2251-2261
PubMed ID: 16000715
|