Pseudomonas aeruginosa PAO1, PA3291 (tli1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3291
Name
tli1
Replicon chromosome
Genomic location 3684163 - 3684717 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251981.1
GI 15598487
Affymetrix PA3291_at
DNASU PaCD00007452
Entrez 882454
GenBank AAG06679.1
INSDC AAG06679.1
NCBI Locus Tag PA3291
protein_id(GenBank) gb|AAG06679.1|AE004751_5|gnl|PseudoCAP|PA3291
TIGR NTL03PA03291
UniParc UPI00000C5996
UniProtKB Acc Q9HYV2
UniProtKB ID Q9HYV2_PSEAE
UniRef100 UniRef100_Q9HYV2
UniRef50 UniRef50_Q9HYV2
UniRef90 UniRef90_Q9HYV2

Product

Feature Type CDS
Coding Frame 1
Product Name
Tli1
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 5.94
Kyte-Doolittle Hydrophobicity Value -0.246
Molecular Weight (kDa) 20.4
Isoelectric Point (pI) 8.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 13 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002323 (150 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3291
Search term: tli1
Search term: Tli1

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors.
Russell AB, LeRoux M, Hathazi K, Agnello DM, Ishikawa T, Wiggins PA, Wai SN, Mougous JD
Nature 2013 Apr 25;496(7446):508-12
PubMed ID: 23552891