Pseudomonas aeruginosa PAO1, PA3351 (flgM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3351
Name
flgM
Synonym: flgM
Replicon chromosome
Genomic location 3762804 - 3763127 (+ strand)
Transposon Mutants in orthologs 2 transposon mutants in orthologs
CommentFlgM protein physically interacts with the alternative sigma factor FliA (PA1455)

Cross-References

RefSeq NP_252041.1
GI 15598547
Affymetrix PA3351_at
DNASU PaCD00007468
Entrez 882518
GenBank AAG06739.1
INSDC AAG06739.1
NCBI Locus Tag PA3351
protein_id(GenBank) gb|AAG06739.1|AE004757_8|gnl|PseudoCAP|PA3351
TIGR NTL03PA03351
UniParc UPI0000052C48
UniProtKB Acc Q9HYP5
UniProtKB ID Q9HYP5_PSEAE
UniRef100 UniRef100_W0YSZ7
UniRef50 UniRef50_A4VJC4
UniRef90 UniRef90_W0YSZ7

Product

Feature Type CDS
Coding Frame 1
Product Name
FlgM
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -1.01
Kyte-Doolittle Hydrophobicity Value -0.594
Molecular Weight (kDa) 11.3
Isoelectric Point (pI) 5.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB
Category Flagella
Evidence
Host Organism
Notes
Reference

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 47 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002277 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3351
Search term: flgM
Search term: FlgM

Human Homologs

References

Identification and functional characterization of flgM, a gene encoding the anti-sigma 28 factor in Pseudomonas aeruginosa.
Frisk A, Jyot J, Arora SK, Ramphal R
J Bacteriol 2002 Mar;184(6):1514-21
PubMed ID: 11872701