Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3479
|
Name |
rhlA
|
Replicon | chromosome |
Genomic location | 3892121 - 3893008 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | RhlA condenses two beta-hyroxydecanoly-ACPs to form the beta-hydroxydecanoly-beta-hydroxyldecanoate moiety of rhamnolipids |
RefSeq | NP_252169.1 |
GI | 15598675 |
Affymetrix | PA3479_rhlA_at |
DNASU | PaCD00007528 |
Entrez | 878955 |
GenBank | AAG06867.1 |
INSDC | AAG06867.1 |
NCBI Locus Tag | PA3479 |
protein_id(GenBank) | gb|AAG06867.1|AE004768_12|gnl|PseudoCAP|PA3479 |
TIGR | NTL03PA03479 |
UniParc | UPI0000133874 |
UniProtKB Acc | Q51559 |
UniProtKB ID | RHLA_PSEAE |
UniRef100 | UniRef100_Q51559 |
UniRef50 | UniRef50_Q51559 |
UniRef90 | UniRef90_Q51559 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
rhamnosyltransferase chain A
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | 2.45 |
Kyte-Doolittle Hydrophobicity Value | -0.180 |
Molecular Weight (kDa) | 33.0 |
Isoelectric Point (pI) | 7.46 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | PseudoCAP |
Category | Rhamnolipid biosynthesis |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Homo sapiens |
Notes | In vitro biofilms of P. aeruginosa PAO1 rhlA mutants yield fewer necrotic PMNs than wild-type PAO1. |
Reference | 19594494 |
Source 2 | |
Database | VFDB : VF0089 |
Category | Rhamnolipid biosynthesis |
Evidence |
|
Host Organism | |
Notes | |
Reference | |
Source 3 | |
Database | PseudoCAP |
Category | Rhamnolipid biosynthesis |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Mus musculus |
Notes | |
Infection model | pulmonary Infection model |
Infection model | foreign-body Infection model |
Reference | 19594494 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 22 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002163 (333 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3479
Search term: rhlA
Search term: rhamnosyltransferase chain A
|
RhlA converts beta-hydroxyacyl-acyl carrier protein intermediates in fatty acid synthesis to the beta-hydroxydecanoyl-beta-hydroxydecanoate component of rhamnolipids in Pseudomonas aeruginosa.
Zhu K, Rock CO
J Bacteriol 2008 May;190(9):3147-54
PubMed ID: 18326581
|