Pseudomonas aeruginosa PAO1, PA3526 (motY)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3526
Name
motY
Replicon chromosome
Genomic location 3945997 - 3946962 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252216.1
GI 15598722
Affymetrix PA3526_at
Entrez 878873
GenBank AAG06914.1
INSDC AAG06914.1
NCBI Locus Tag PA3526
protein_id(GenBank) gb|AAG06914.1|AE004773_3|gnl|PseudoCAP|PA3526
TIGR NTL03PA03526
UniParc UPI00000C5A54
UniProtKB Acc Q9HY83
UniProtKB ID Q9HY83_PSEAE
UniRef100 UniRef100_U8NPL8
UniRef50 UniRef50_Q87XM2
UniRef90 UniRef90_A6V1S0

Product

Feature Type CDS
Coding Frame 1
Product Name
MotY
Product Name Confidence: Class 1
Synonyms probable outer membrane protein precursor
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 9.66
Kyte-Doolittle Hydrophobicity Value -0.336
Molecular Weight (kDa) 35.1
Isoelectric Point (pI) 10.32

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB
Category Flagella
Evidence
Host Organism
Notes
Reference

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 349 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002139 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3526
Search term: motY
Search term: MotY

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
MotY, a component of the sodium-type flagellar motor.
McCarter LL
J Bacteriol 1994 Jul;176(14):4219-25
PubMed ID: 8021208
The complex flagellar torque generator of Pseudomonas aeruginosa.
Doyle TB, Hawkins AC, McCarter LL
J Bacteriol 2004 Oct;186(19):6341-50
PubMed ID: 15375113