Pseudomonas aeruginosa PAO1, PA3585 (glpM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3585
Name
glpM
Replicon chromosome
Genomic location 4018112 - 4018441 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252275.1
GI 15598781
Affymetrix PA3585_glpM_at
Entrez 880180
GenBank AAG06973.1
NCBI Locus Tag PA3585
protein_id(GenBank) gb|AAG06973.1|AE004779_5|gnl|PseudoCAP|PA3585
TIGR NTL03PA03585
UniProtKB Acc P52112
UniProtKB ID GLPM_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
membrane protein GlpM
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 5.46
Kyte-Doolittle Hydrophobicity Value 1.175
Molecular Weight (kDa) 12.0
Isoelectric Point (pI) 10.17

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 31 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002085 (443 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3585
Search term: glpM

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Identification of Pseudomonas aeruginosa glpM, whose gene product is required for efficient alginate biosynthesis from various carbon sources.
Schweizer HP, Po C, Bacic MK
J Bacteriol 1995 Aug;177(16):4801-4
PubMed ID: 7642508