Pseudomonas aeruginosa PAO1, PA3633 (ygbP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3633
Name
ygbP
Replicon chromosome
Genomic location 4067604 - 4068308 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_252323.1
GI 15598829
Affymetrix PA3633_at
DNASU PaCD00007594
Entrez 880461
GenBank AAG07021.1
INSDC AAG07021.1
NCBI Locus Tag PA3633
protein_id(GenBank) gb|AAG07021.1|AE004783_6|gnl|PseudoCAP|PA3633
TIGR NTL03PA03633
UniParc UPI000012D927
UniProtKB Acc P57707
UniProtKB ID ISPD_PSEAE
UniRef100 UniRef100_P57707
UniRef50 UniRef50_P57707
UniRef90 UniRef90_P57707

Product

Feature Type CDS
Coding Frame 1
Product Name
4-diphosphocytidyl-2-C-methylerythritol synthase
Product Name Confidence: Class 2
Synonyms YgbP protein
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.89
Kyte-Doolittle Hydrophobicity Value -0.121
Molecular Weight (kDa) 25.6
Isoelectric Point (pI) 5.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 519 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002041 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3633
Search term: ygbP

Human Homologs

References

Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol.
Rohdich F, Wungsintaweekul J, Fellermeier M, Sagner S, Herz S, Kis K, Eisenreich W, Bacher A, Zenk MH
Proc Natl Acad Sci U S A 1999 Oct 12;96(21):11758-63
PubMed ID: 10518523