Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3719
|
Name |
armR
|
Replicon | chromosome |
Genomic location | 4165719 - 4165880 (- strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | ArmR is an antirepressor for MexR |
RefSeq | NP_252408.1 |
GI | 15598914 |
Affymetrix | PA3719_at |
Entrez | 880376 |
GenBank | AAG07106.1 |
INSDC | AAG07106.1 |
NCBI Locus Tag | PA3719 |
protein_id(GenBank) | gb|AAG07106.1|AE004791_3|gnl|PseudoCAP|PA3719 |
TIGR | NTL03PA03719 |
UniParc | UPI00000C5ADA |
UniProtKB Acc | Q9HXS2 |
UniProtKB ID | Q9HXS2_PSEAE |
UniRef100 | UniRef100_W0YX37 |
UniRef50 | UniRef50_W0YX37 |
UniRef90 | UniRef90_W0YX37 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
antirepressor for MexR, ArmR
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | 4.22 |
Kyte-Doolittle Hydrophobicity Value | -1.160 |
Molecular Weight (kDa) | 6.1 |
Isoelectric Point (pI) | 10.72 |
Individual Mappings | |
Additional evidence for subcellular localization |
Identified using the Resistance Gene Identifier (RGI)
Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
ArmR | ArmR, a 53-amino-acid antirepressor, allosterically inhibits MexR dimer-DNA binding by occupying a hydrophobic binding cavity within the center of the MexR dimer. ArmR up-regulation and MexR-ArmR complex formation have previously been shown to upregulate MexAB-OprM. [PMID:17545281, PMID:18812515] | ARO:3004056 | protein homolog model | Perfect | 106.3 | 100.0 | 3.2.5 |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
3ECH | Transcription, Transcription regulation | 08/30/08 | The MarR-family repressor MexR in complex with its antirepressor ArmR | Pseudomonas aeruginosa | 1.802 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in one genus
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001964 (205 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3719
Search term: armR
Search term: antirepressor for MexR, ArmR
|
Protein modulator of multidrug efflux gene expression in Pseudomonas aeruginosa.
Daigle DM, Cao L, Fraud S, Wilke MS, Pacey A, Klinoski R, Strynadka NC, Dean CR, Poole K
J Bacteriol 2007 Aug;189(15):5441-51
PubMed ID: 17545281
|