Pseudomonas aeruginosa PAO1, PA3777 (xseA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3777
Name
xseA
Replicon chromosome
Genomic location 4235220 - 4236599 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_252466.1
GI 15598972
Affymetrix PA3777_xseA_at
Entrez 878333
GenBank AAG07164.1
INSDC AAG07164.1
NCBI Locus Tag PA3777
protein_id(GenBank) gb|AAG07164.1|AE004796_9|gnl|PseudoCAP|PA3777
TIGR NTL03PA03777
UniParc UPI000012A2F2
UniProtKB Acc Q9HXL8
UniProtKB ID EX7L_PSEAE
UniRef100 UniRef100_Q9HXL8
UniRef50 UniRef50_Q886X9
UniRef90 UniRef90_Q9HXL8

Product

Feature Type CDS
Coding Frame 1
Product Name
exodeoxyribonuclease VII large subunit
Product Name Confidence: Class 2
Synonyms Exonuclease VII
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 20.62
Kyte-Doolittle Hydrophobicity Value -0.298
Molecular Weight (kDa) 51.2
Isoelectric Point (pI) 11.40

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 530 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001887 (552 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3777
Search term: xseA

References

Subunit structure of Escherichia coli exonuclease VII.
Vales LD, Rabin BA, Chase JW
J Biol Chem 1982 Aug 10;257(15):8799-805
PubMed ID: 6284744
Isolation and preliminary characterization of Escherichia coli mutants deficient in exonuclease VII.
Vales LD, Rabin BA, Chase JW
J Bacteriol 1983 Sep;155(3):1116-22
PubMed ID: 6350262
Escherichia coli exonuclease VII. Cloning and sequencing of the gene encoding the large subunit (xseA).
Chase JW, Rabin BA, Murphy JB, Stone KL, Williams KR
J Biol Chem 1986 Nov 15;261(32):14929-35
PubMed ID: 3021756