Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3885
|
Name |
tpbA
|
Replicon | chromosome |
Genomic location | 4350834 - 4351490 (+ strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_252574.1 |
GI | 15599080 |
Affymetrix | PA3885_at |
DNASU | PaCD00007691 |
Entrez | 878776 |
GenBank | AAG07272.1 |
INSDC | AAG07272.1 |
NCBI Locus Tag | PA3885 |
protein_id(GenBank) | gb|AAG07272.1|AE004805_10|gnl|PseudoCAP|PA3885 |
TIGR | NTL03PA03885 |
UniParc | UPI00000C5B5A |
UniProtKB Acc | Q9HXC7 |
UniProtKB ID | Q9HXC7_PSEAE |
UniRef100 | UniRef100_Q9HXC7 |
UniRef50 | UniRef50_Q9HXC7 |
UniRef90 | UniRef90_Q9HXC7 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
protein tyrosine phosphatase TpbA
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | 0.59 |
Kyte-Doolittle Hydrophobicity Value | -0.111 |
Molecular Weight (kDa) | 24.0 |
Isoelectric Point (pI) | 7.20 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4R0S | HYDROLASE | 08/01/14 | Crystal structure of P. aeruginosa TpbA | Pseudomonas aeruginosa PAO1 | 2.03 | X-RAY DIFFRACTION | 100.0 |
2M3V | HYDROLASE | 01/26/13 | Solution structure of tyrosine phosphatase related to biofilm formation A (TpbA) from Pseudomonas aeruginosa | Pseudomonas aeruginosa | NOT | SOLUTION NMR | 97.4 |
4R0T | HYDROLASE | 08/01/14 | Crystal structure of P. aeruginosa TpbA (C132S) in complex with pTyr | Pseudomonas aeruginosa PAO1 | 2.603 | X-RAY DIFFRACTION | 99.5 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 32 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001786 (406 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3885
Search term: tpbA
Search term: protein tyrosine phosphatase TpbA
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Connecting quorum sensing, c-di-GMP, pel polysaccharide, and biofilm formation in Pseudomonas aeruginosa through tyrosine phosphatase TpbA (PA3885).
Ueda A, Wood TK
PLoS Pathog 2009 Jun;5(6):e1000483
PubMed ID: 19543378
|
Expression, purification, crystallization and preliminary crystallographic analysis of PA3885 (TpbA) from Pseudomonas aeruginosa PAO1.
Yang W, Li K, Bai Y, Zhou R, Zhou W, Bartlam M
Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 Nov 1;66(Pt 11):1473-6
PubMed ID: 21045298
|