Pseudomonas aeruginosa PAO1, PA3889 (opuCC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3889
Name
opuCC
Replicon chromosome
Genomic location 4355266 - 4356201 (+ strand)
Transposon Mutants 6 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
CommentBroad-spectrum QAC-transporter activated by hyperosmolarity
CommentBroad-spectrum QAC-transporter activated by hyperosmolarity

Cross-References

RefSeq NP_252578.1
GI 15599084
Affymetrix PA3889_at
DNASU PaCD00007694
Entrez 878805
GenBank AAG07276.1
INSDC AAG07276.1
NCBI Locus Tag PA3889
protein_id(GenBank) gb|AAG07276.1|AE004806_3|gnl|PseudoCAP|PA3889
TIGR NTL03PA03889
UniParc UPI00000C5B5D
UniProtKB Acc Q9HXC4
UniProtKB ID Q9HXC4_PSEAE
UniRef100 UniRef100_A0A069QBS6
UniRef50 UniRef50_D8IQW6
UniRef90 UniRef90_A6V0L7

Product

Feature Type CDS
Coding Frame 1
Product Name
OpuC ABC transporter, periplasmic substrate-binding protein, OpuCC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.37
Kyte-Doolittle Hydrophobicity Value -0.295
Molecular Weight (kDa) 34.7
Isoelectric Point (pI) 5.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 249 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001781 (491 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3889
Search term: opuCC

Human Homologs

References

Characterization of a chimeric proU operon in a subtilin-producing mutant of Bacillus subtilis 168.
Lin Y, Hansen JN
J Bacteriol 1995 Dec;177(23):6874-80
PubMed ID: 7592481
Characterization of the osmoprotectant transporter OpuC from Pseudomonas syringae and demonstration that cystathionine-beta-synthase domains are required for its osmoregulatory function.
Chen C, Beattie GA
J Bacteriol 2007 Oct;189(19):6901-12
PubMed ID: 17660277