Pseudomonas aeruginosa PAO1, PA4002 (rodA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4002
Name
rodA
Synonym: mrdB
Replicon chromosome
Genomic location 4482261 - 4483364 (- strand)

Cross-References

RefSeq NP_252691.1
GI 15599197
Affymetrix PA4002_rodA_at
Entrez 878947
GenBank AAG07389.1
INSDC AAG07389.1
NCBI Locus Tag PA4002
protein_id(GenBank) gb|AAG07389.1|AE004817_13|gnl|PseudoCAP|PA4002
TIGR NTL03PA04002
UniParc UPI00000D4286
UniProtKB Acc G3XD88
UniProtKB ID G3XD88_PSEAE
UniRef100 UniRef100_W0YW74
UniRef50 UniRef50_P44468
UniRef90 UniRef90_A6V0A8

Product

Feature Type CDS
Coding Frame 1
Product Name
rod shape-determining protein
Product Name Confidence: Class 2
Synonyms RodA protein
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 11.87
Kyte-Doolittle Hydrophobicity Value 0.847
Molecular Weight (kDa) 40.0
Isoelectric Point (pI) 10.32

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 575 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001681 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4002
Search term: rodA

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Molecular cloning and characterization of the genes (pbpA and rodA) responsible for the rod shape of Escherichia coli K-12: analysis of gene expression with transposon Tn5 mutagenesis and protein synthesis directed by constructed plasmids.
Asoh S, Matsuzawa H, Matsuhashi M, Ohta T
J Bacteriol 1983 Apr;154(1):10-6
PubMed ID: 6300030
Identification of the rodA gene product of Escherichia coli.
Stoker NG, Pratt JM, Spratt BG
J Bacteriol 1983 Aug;155(2):854-9
PubMed ID: 6348029