Pseudomonas aeruginosa PAO1, PA4101 (bfmR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4101
Name
bfmR
Replicon chromosome
Genomic location 4585149 - 4585889 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_252790.1
GI 15599296
Affymetrix PA4101_at
Entrez 878752
GenBank AAG07488.1
INSDC AAG07488.1
NCBI Locus Tag PA4101
protein_id(GenBank) gb|AAG07488.1|AE004826_6|gnl|PseudoCAP|PA4101
TIGR NTL03PA04101
UniParc UPI00000C5C0F
UniProtKB Acc Q9HWS7
UniProtKB ID Q9HWS7_PSEAE
UniRef100 UniRef100_W0YZI7
UniRef50 UniRef50_G2DHI0
UniRef90 UniRef90_B1J6F0

Product

Feature Type CDS
Coding Frame 1
Product Name
BfmR
Product Name Confidence: Class 1
Synonyms Biofilm maturation Regulator
Evidence for Translation
Charge (pH 7) -2.58
Kyte-Doolittle Hydrophobicity Value -0.212
Molecular Weight (kDa) 28.0
Isoelectric Point (pI) 6.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 623 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005148 (385 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4101
Search term: bfmR
Search term: BfmR

Human Homologs

References

A novel signaling network essential for regulating Pseudomonas aeruginosa biofilm development.
Petrova OE, Sauer K
PLoS Pathog 2009 Nov;5(11):e1000668
PubMed ID: 19936057
Genome-Wide Mapping Reveals Complex Regulatory Activities of BfmR in Pseudomonas aeruginosa.
Fan K, Cao Q, Lan L
Microorganisms 2021 Feb 25;9(3)
PubMed ID: 33668961