Pseudomonas aeruginosa PAO1, PA4102 (bfmS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4102
Name
bfmS
Replicon chromosome
Genomic location 4585886 - 4587190 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_252791.1
GI 15599297
Affymetrix PA4102_at
Entrez 878756
GenBank AAG07489.1
INSDC AAG07489.1
NCBI Locus Tag PA4102
protein_id(GenBank) gb|AAG07489.1|AE004826_7|gnl|PseudoCAP|PA4102
TIGR NTL03PA04102
UniParc UPI00000C5C10
UniProtKB Acc Q9HWS6
UniProtKB ID Q9HWS6_PSEAE
UniRef100 UniRef100_W0YYB9
UniRef50 UniRef50_F8GQK7
UniRef90 UniRef90_K1E0D8

Product

Feature Type CDS
Coding Frame 1
Product Name
BfmS
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 1.09
Kyte-Doolittle Hydrophobicity Value -0.080
Molecular Weight (kDa) 47.8
Isoelectric Point (pI) 7.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 616 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005149 (398 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4102
Search term: bfmS
Search term: BfmS

Human Homologs

References

Identification of the site of phosphorylation on the osmosensor, EnvZ, of Escherichia coli.
Roberts DL, Bennett DW, Forst SA
J Biol Chem 1994 Mar 25;269(12):8728-33
PubMed ID: 8132603
A Coxiella burnetii gene encodes a sensor-like protein.
Mo YY, Mallavia LP
Gene 1994 Dec 30;151(1-2):185-90
PubMed ID: 7828872
A novel signaling network essential for regulating Pseudomonas aeruginosa biofilm development.
Petrova OE, Sauer K
PLoS Pathog 2009 Nov;5(11):e1000668
PubMed ID: 19936057
Genome-Wide Mapping Reveals Complex Regulatory Activities of BfmR in Pseudomonas aeruginosa.
Fan K, Cao Q, Lan L
Microorganisms 2021 Feb 25;9(3)
PubMed ID: 33668961