Pseudomonas aeruginosa PAO1, PA4144

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4144
Name
Synonym: opmK
Replicon chromosome
Genomic location 4636298 - 4637713 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252833.1
GI 15599339
Affymetrix PA4144_at
Entrez 880262
GenBank AAG07531.1
INSDC AAG07531.1
NCBI Locus Tag PA4144
protein_id(GenBank) gb|AAG07531.1|AE004831_3|gnl|PseudoCAP|PA4144
TIGR NTL03PA04144
UniParc UPI00000C5C35
UniProtKB Acc Q9HWN7
UniProtKB ID Q9HWN7_PSEAE
UniRef100 UniRef100_Q9HWN7
UniRef50 UniRef50_Q02SW0
UniRef90 UniRef90_Q02SW0

Product

Feature Type CDS
Coding Frame 1
Product Name
probable outer membrane protein precursor
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -0.63
Kyte-Doolittle Hydrophobicity Value -0.244
Molecular Weight (kDa) 50.6
Isoelectric Point (pI) 6.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 316 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001555 (681 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4144

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Secretion of cyclolysin, the calmodulin-sensitive adenylate cyclase-haemolysin bifunctional protein of Bordetella pertussis.
Glaser P, Sakamoto H, Bellalou J, Ullmann A, Danchin A
EMBO J 1988 Dec 1;7(12):3997-4004
PubMed ID: 2905265