Pseudomonas aeruginosa PAO1, PA4202 (nmoA)

Cytoplasmic Membrane
Outer Membrane
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
Replicon chromosome
Genomic location 4702042 - 4703097 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs


RefSeq NP_252891.1
GI 15599397
Affymetrix PA4202_at
Entrez 879034
GenBank AAG07589.1
INSDC AAG07589.1
NCBI Locus Tag PA4202
protein_id(GenBank) gb|AAG07589.1|AE004836_8|gnl|PseudoCAP|PA4202
UniParc UPI00000C5C6F
UniProtKB Acc Q9HWH9
UniRef100 UniRef100_Q9HWH9
UniRef50 UniRef50_Q9HWH9
UniRef90 UniRef90_Q9HWH9


Feature Type CDS
Coding Frame 1
Product Name
nitronate monooxygenase NmoA
Product Name Confidence: Class 1
Synonyms nitronate monooxygenase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.88
Kyte-Doolittle Hydrophobicity Value 0.144
Molecular Weight (kDa) 36.8
Isoelectric Point (pI) 8.07

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4Q4K OXIDOREDUCTASE 04/14/14 Crystal structure of nitronate monooxygenase from Pseudomonas aeruginosa PAO1 PSEUDOMONAS AERUGINOSA 1.44 X-RAY DIFFRACTION 100.0
4QIU OXIDOREDUCTASE 06/02/14 Crystal structure of Nitroalkane Oxidase from Pseudomonas aeruginosa in Mutant complex form PSEUDOMONAS AERUGINOSA 1.401 X-RAY DIFFRACTION 99.7
4QIS OXIDOREDUCTASE 06/02/14 Crystal structure of Nitroalkane Oxidase from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 1.906 X-RAY DIFFRACTION 100.0
4QIT OXIDOREDUCTASE 06/02/14 Crystal structure of Nitroalkane Oxidase from Pseudomonas aeruginosa in mutant complex form PSEUDOMONAS AERUGINOSA 1.4 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 361 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001505 (485 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: PA4202
Search term: nmoA


Unique primary structure of 2-nitropropane dioxygenase from Hansenula mrakii.
Tchorzewski M, Kurihara T, Esaki N, Soda K
Eur. J. Biochem. 1994 Dec;226(3):841-6
PubMed ID: 7813473
The combined structural and kinetic characterization of a bacterial nitronate monooxygenase from Pseudomonas aeruginosa PAO1 establishes NMO class I and II.
Salvi F, Agniswamy J, Yuan H, Vercammen K, Pelicaen R, Cornelis P, Spain JC, Weber IT, Gadda G
J. Biol. Chem. 2014 Aug;289(34):23764-75
PubMed ID: 25002579